The Bulk Dosing feature in Benchling’s In Vivo application allows users to quickly and efficiently record dosing for multiple animals at once. This feature is particularly useful in scenarios where all animals receive the same treatment at the same time, and eliminates the need for individually recording each dose event.
To administer treatment doses navigate the Doses page in a study for which you have write access and click on the button to Record Dose to go through the dosing steps defining the treatments, animals and any comments to be recorded for this dosing event.
Selecting treatments
The first step is to select the treatments that will be administered. You can select as many treatments as required however, if animals are assigned to groups with more than one treatment assigned, it will have both of these treatments administered. If only one of these treatments are to be administered, select that single treatment and complete the process as many times as needed.
Note: Animals will only receive treatments that have been assigned to the group they are in.
Confirming animals
After you have selected treatments you must confirm the animals to proceed to dosing. All animals that are in groups that have at least one of the selected treatments will be available and you can select all by clicking the checkbox at the top left of the table or use filters and sorts to find the animals to select to proceed to dosing.
Recording doses
The last step is to confirm the date and time and the comment on the doses that will be recorded. This page automatically calculates the dose and dose volume based on study design using the latest body weight available for this animal. This tool is not designed for real time usage, please continue to use workflow for real time recording of body weights and dosing calculations with timestamps in this situation.
Points to Note:
- You cannot record a new weight at dosing for calculations
- any animals that require body weight for dosing that do not have any body weights recorded will be automatically excluded from dosing
- any deceased animals will be automatically excluded from dosing
- Although the date and time are changed the body weight used for calculations is not updated to reflect the body weight on the selected date.
Managing historical doses
Although doses cannot be edited once created if these have been administered in error a user with write access to the study can use the bulk action to delete these from the doses table.