A Study is a schematized object that exists within the Studies application icon, and also within its associated Project or Folder. Other types of Benchling objects and tasks can be associated with a Study, and are aggregated on a tab of the Study as Study Items. Benchling offers two main types of study frameworks—Custom Studies and Typed Studies—to assist researchers in compiling relevant Study information..
This guide focuses on how to create Process Development Studies (PD Studies), a category of Typed Studies used for Benchling Bioprocess.
How to Create a PD Study
Click through the steps below to learn how to create a PD Study with your Recipe.
Prerequisite
Before users can create a PD Study object, a PD Study schema must be configured for users to select from. Learn more about configuring Study Schemas here. Make sure to select Process Development for the Study Type to be able to use the Study with a Recipe.
Step 1: Create the Study
Use the Global Create icon to navigate to the Study section, and click on the Study schema that you’d like to use.
Note: in order to execute your Recipe, you must pick a Study schema that has been designated as a Process Development Study type
Step 2: Specify Study Metadata
In the Create Study modal, use the textboxes to name your Study and designate what folder it belongs to.
- Note: The general access policies assigned on the Project or Folder will apply to the Study within the Project or Folder as well. You must have at least Write access to a Project or Folder to create a Study within it.
Fill out any of the required fields that are part of the Study schema. Then use the Recipe dropdown to designate which Recipe will be used for your Study.
Optionally, use the Description textbox to provide information about the Study. This description will appear on the Study Overview tab once the Study has been created.
Once finished, click the Next button.
Step 3: Design Experiment - Conditions and Replicates
At the top of the modal, use the Experiment configuration section to define the number of Conditions and Replicates to execute.
Click the + Add condition button to add a single condition. Click the the ▾ icon if you want to add multiple conditions and replicates at once.
Step 4: Design Experiment - Unit Operation Values
Use the Materials, Parameters, and Equipment tables to designate what values you want to change for each condition. If you do not enter a value in the Condition column, the setpoint during batch execution will default to the value listed in the “setpoint” column (i.e., from the original Recipe).
Use the list of Unit Operations on the left to click into every Unit Operation where you need to define Conditions.
Once finished updating values for each Condition across Unit Operations, click the Proceed to execution button.
Note: Once you proceed to execution, you will not be able to edit the number of Conditions, number of Replicates, or the list of defined Materials, Parameters, and Equipment setpoints for each Condition. However, during execution you will be able to enter a confirmed value and actual values for the Unit Operation definitions (i.e., Materials, Parameters, and Equipment).
Now that the study is configured, the PD Study dashboard provides a landing page with multiple tabs to view the study status, quickly access Worksheets, and review the overall experiment design. For more information, please refer to Bioprocess Study Navigation article here.